3QPV

PFKFB3 trapped in a phospho-enzyme intermediate state

Summary for 3QPV

Entry DOI	10.2210/pdb3qpv/pdb
Related	3QPU 3QPW
Descriptor	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, 2,6-di-O-phosphono-beta-D-fructofuranose, PHOSPHONIC ACID, ... (6 entities in total)
Functional Keywords	kinase/bisphosphatase, transferase, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	60803.59
Authors	Cavalier, M.C.,Kim, S.G.,Neau, D.,Lee, Y.H. (deposition date: 2011-02-14, release date: 2012-02-08, Last modification date: 2024-02-21)
Primary citation	Cavalier, M.C.,Kim, S.G.,Neau, D.,Lee, Y.H. Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function. Proteins, 80:1143-1153, 2012 Cited by PubMed: 22275052 DOI: 10.1002/prot.24015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation