3QFD
Human Class I MHC HLA-A2 in complex with Mart-1(27-35) nonameric peptide
Summary for 3QFD
Entry DOI | 10.2210/pdb3qfd/pdb |
Related | 2GUO |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Mart-1(27-35) peptide, ... (6 entities in total) |
Functional Keywords | mart-1 peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, melanoma, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 6 |
Total formula weight | 89693.63 |
Authors | Borbulevych, O.Y.,Baker, B.M. (deposition date: 2011-01-21, release date: 2011-09-28, Last modification date: 2011-12-14) |
Primary citation | Insaidoo, F.K.,Borbulevych, O.Y.,Hossain, M.,Santhanagopolan, S.M.,Baxter, T.K.,Baker, B.M. Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN. J.Biol.Chem., 286:40163-40173, 2011 Cited by PubMed: 21937447DOI: 10.1074/jbc.M111.283564 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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