3QCU

Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0)

Summary for 3QCU

Entry DOI	10.2210/pdb3qcu/pdb
Related	3QCT 3QCV
Descriptor	LT3015 antibody Fab fragment, heavy chain, LT3015 antibody Fab fragment, light chain, (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, ... (4 entities in total)
Functional Keywords	antibody, lysophosphatidic acid binding, immune system
Biological source	Homo sapiens (human) More
Cellular location	Secreted : P01834
Total number of polymer chains	4
Total formula weight	96521.79
Authors	Fleming, J.K.,Wojciak, J.M.,Campbell, M.-A.,Huxford, T. (deposition date: 2011-01-17, release date: 2011-03-30, Last modification date: 2023-09-13)
Primary citation	Fleming, J.K.,Wojciak, J.M.,Campbell, M.A.,Huxford, T. Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408:462-476, 2011 Cited by PubMed: 21392506 DOI: 10.1016/j.jmb.2011.02.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.979 Å)

Structure validation