3Q80

Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME

Summary for 3Q80

Entry DOI	10.2210/pdb3q80/pdb
Related	3OKR 3Q7U
Descriptor	2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	tb structural genomics consortium, tbsgc, rossmann fold, 2-c-methyl-d-erythritol 4-phosphate cytidyltransferase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	49359.79
Authors	Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Ioerger, T.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-01-05, release date: 2011-05-04, Last modification date: 2023-09-13)
Primary citation	Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Ioerger, T.R.,Sacchettini, J.C. Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target Proteins, 2011
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation