3PXK

FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH Pyrrolo[2,3-d]thiazole

Summary for 3PXK

• Entry DOI: 10.2210/pdb3pxk/pdb
• Descriptor: PTK2 protein, 6-(4,4-dimethylpent-2-ynyl)-4~{H}-pyrrolo[2,3-d][1,3]thiazole, SULFATE ION, ... (4 entities in total)
• Functional Keywords: tyrosine protein kinase, transferase, atp binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65141.14

Authors

Koolman, H.,Heinrich, T.,Musil, D. (deposition date: 2010-12-10, release date: 2011-12-21, Last modification date: 2023-09-13)

• Primary citation: Koolman, H.,Heinrich, T.,Musil, D.; Co-crystal Structures of FAK with an Unprecedented Pyrrolo[2,3-d]thiazole; To be Published,

Experimental method

X-RAY DIFFRACTION (1.79 Å)