3PG7
Crystal structure of the H. sapiens NF1 SEC-PH domain (del1750 mutant)
Summary for 3PG7
| Entry DOI | 10.2210/pdb3pg7/pdb |
| Descriptor | Neurofibromin, PHOSPHATIDYLETHANOLAMINE, PYROPHOSPHATE 2-, ... (4 entities in total) |
| Functional Keywords | sec lipid binding domain, ph domain, lipid binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 60481.14 |
| Authors | Welti, S.,D'Angelo, I.,Scheffzek, K. (deposition date: 2010-10-31, release date: 2010-12-08, Last modification date: 2011-07-13) |
| Primary citation | Welti, S.,Kuhn, S.,D'Angelo, I.,Brugger, B.,Kaufmann, D.,Scheffzek, K. Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin. Hum.Mutat., 32:191-197, 2011 Cited by PubMed: 21089070DOI: 10.1002/humu.21405 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.189 Å) |
Structure validation
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