3PF3

Crystal structure of a mutant (C202A) of Triosephosphate isomerase from Giardia lamblia derivatized with MMTS

Summary for 3PF3

Entry DOI	10.2210/pdb3pf3/pdb
Related	2DP3
Descriptor	Triosephosphate isomerase, SULFATE ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	triosephosphate isomerase, giardia, isomerase, alpha/beta barrel, thiomethylation, alfa/beta barrel, thiomethylation of cys14, cys222, cys 228
Biological source	Giardia intestinalis (Giardia intestinalis)
Total number of polymer chains	1
Total formula weight	28739.07
Authors	Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Santoyo, A.,Reyes-Vivas, H. (deposition date: 2010-10-27, release date: 2011-06-22, Last modification date: 2023-09-06)
Primary citation	Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Alcantara, G.,Oria-Hernandez, J.,Gutierrez-Castrellon, P.,Perez-Hernandez, G.,Mora-Ide, L.,Castillo-Villanueva, A.,Garcia-Torres, I.,Mendez, S.T.,Gomez-Manzo, S.,Torres-Arroyo, A.,Lopez-Velazquez, G.,Reyes-Vivas, H. Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: A study for antiparasitic drug design. Proteins, 79:2711-2724, 2011 Cited by PubMed: 21786322 DOI: 10.1002/prot.23100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.098 Å)

Structure validation