3P1O
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilisator Fusicoccin A
Summary for 3P1O
Entry DOI | 10.2210/pdb3p1o/pdb |
Related | 2O98 3IQV 3M50 3P1N 3P1P 3P1Q 3P1R 3P1S |
Descriptor | 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, FUSICOCCIN, ... (7 entities in total) |
Functional Keywords | helical protein, phosphoprotein, adapter protein, peptide binding protein, nucleus |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P31947 Cell membrane ; Multi-pass membrane protein : Q9NPC2 |
Total number of polymer chains | 2 |
Total formula weight | 28212.39 |
Authors | Anders, C.,Higuchi, Y.,Schumacher, B.,Thiel, P.,Kato, N.,Ottmann, C. (deposition date: 2010-09-30, release date: 2011-10-12, Last modification date: 2023-12-06) |
Primary citation | Anders, C.,Higuchi, Y.,Koschinsky, K.,Bartel, M.,Schumacher, B.,Thiel, P.,Nitta, H.,Preisig-Muller, R.,Schlichthorl, G.,Renigunta, V.,Ohkanda, J.,Daut, J.,Kato, N.,Ottmann, C. A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20:583-593, 2013 Cited by PubMed: 23601647DOI: 10.1016/j.chembiol.2013.03.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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