3OZ1
cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac066
Summary for 3OZ1
Entry DOI | 10.2210/pdb3oz1/pdb |
Related | 3MUP |
Descriptor | Baculoviral IAP repeat-containing protein 2, ZINC ION, (3S,6S,7R,9aS)-7-[2-(benzylamino)ethyl]-N-(diphenylmethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, ... (4 entities in total) |
Functional Keywords | zinc-finger, caspases, apoptosis inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (Potential): Q13490 |
Total number of polymer chains | 4 |
Total formula weight | 60261.80 |
Authors | Cossu, F.,Malvezzi, F.,Mastrangelo, E.,Canevari, G.,Bolognesi, M.,Milani, M. (deposition date: 2010-09-24, release date: 2010-11-24, Last modification date: 2024-03-20) |
Primary citation | Cossu, F.,Malvezzi, F.,Canevari, G.,Mastrangelo, E.,Lecis, D.,Delia, D.,Seneci, P.,Scolastico, C.,Bolognesi, M.,Milani, M. Recognition of Smac-mimetic compounds by the BIR3 domain of cIAP1 Protein Sci., 2010 Cited by PubMed: 20954235DOI: 10.1002/pro.523 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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