3OTH
Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form
Summary for 3OTH
Entry DOI | 10.2210/pdb3oth/pdb |
Related | 3D0Q 3D0R 3OTG 3OTI |
Descriptor | CalG1, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin alpha3I, ... (4 entities in total) |
Functional Keywords | calicheamicin, tdp, structural genomics, psi-2, protein structure initiative, center for eukaryotic structural genomics, cesg, gt-b fold, glycosyltransferase, transferase-antibiotic complex, enzyme discovery for natural product biosynthesis, natpro, transferase/antibiotic |
Biological source | Micromonospora echinospora (Micromonospora purpurea) |
Total number of polymer chains | 2 |
Total formula weight | 90696.07 |
Authors | Chang, A.,Singh, S.,Bingman, C.A.,Thorson, J.S.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2010-09-11, release date: 2010-12-15, Last modification date: 2017-11-08) |
Primary citation | Chang, A.,Singh, S.,Helmich, K.E.,Goff, R.D.,Bingman, C.A.,Thorson, J.S.,Phillips, G.N. Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108:17649-17654, 2011 Cited by PubMed: 21987796DOI: 10.1073/pnas.1108484108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.301 Å) |
Structure validation
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