3OTE
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I
Summary for 3OTE
| Entry DOI | 10.2210/pdb3ote/pdb |
| Related | 3OTB 3OTC 3OTD |
| Descriptor | tRNA(His) guanylyltransferase (2 entities in total) |
| Functional Keywords | guanylyltransferase, polymerase-like palm domain, catalytic carboxylates, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q9NWX6 |
| Total number of polymer chains | 2 |
| Total formula weight | 63257.88 |
| Authors | Hyde, S.J.,Eckenroth, B.E.,Doublie, S. (deposition date: 2010-09-11, release date: 2010-11-17, Last modification date: 2024-02-21) |
| Primary citation | Hyde, S.J.,Eckenroth, B.E.,Smith, B.A.,Eberley, W.A.,Heintz, N.H.,Jackman, J.E.,Doublie, S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107:20305-20310, 2010 Cited by PubMed: 21059936DOI: 10.1073/pnas.1010436107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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