3OMH
Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
Summary for 3OMH
Entry DOI | 10.2210/pdb3omh/pdb |
Related | 2QCJ 2QCT |
Descriptor | Tyrosine-protein phosphatase non-receptor type 22, Src kinase-associated phosphoprotein 2 (3 entities in total) |
Functional Keywords | hydrolase, tyrosine phosphatase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): Q9Y2R2 Cytoplasm: O75563 |
Total number of polymer chains | 8 |
Total formula weight | 151636.26 |
Authors | Yu, X.,Sun, J.-P.,Zhang, S.,Zhang, Z.-Y. (deposition date: 2010-08-26, release date: 2011-06-29, Last modification date: 2011-09-14) |
Primary citation | Yu, X.,Chen, M.,Zhang, S.,Yu, Z.H.,Sun, J.P.,Wang, L.,Liu, S.,Imasaki, T.,Takagi, Y.,Zhang, Z.Y. Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate. J.Biol.Chem., 286:30526-30534, 2011 Cited by PubMed: 21719704DOI: 10.1074/jbc.M111.254722 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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