3OJY

Crystal Structure of Human Complement Component C8

Summary for 3OJY

• Entry DOI: 10.2210/pdb3ojy/pdb
• Descriptor: Complement component C8 alpha chain, Complement component C8 beta chain, Complement component C8 gamma chain, ... (5 entities in total)
• Functional Keywords: macpf, lipocalin, complement, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P07357 P07358 P07360
• Total number of polymer chains: 3
• Total formula weight: 144917.33

Authors

Lovelace, L.L.,Cooper, C.L.,Sodetz, J.M.,Lebioda, L. (deposition date: 2010-08-23, release date: 2011-04-13, Last modification date: 2023-09-06)

• Primary citation: Lovelace, L.L.,Cooper, C.L.,Sodetz, J.M.,Lebioda, L.; Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.; J.Biol.Chem., 286:17585-17592, 2011; PubMed: 21454577; DOI: 10.1074/jbc.M111.219766

Experimental method

X-RAY DIFFRACTION (2.51 Å)