3O2D

Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody

Summary for 3O2D

Entry DOI	10.2210/pdb3o2d/pdb
Descriptor	ibalizumab light chain, ibalizumab heavy chain, T-cell surface glycoprotein CD4, ... (4 entities in total)
Functional Keywords	immunoglobulin fold, hiv-1 primary receptor, t cell coreceptor, monoclonal antibody, membrane, immune system
Biological source	Mus musculus (mouse) More
Cellular location	Cell membrane; Single-pass type I membrane protein: P01730
Total number of polymer chains	3
Total formula weight	69577.77
Authors	Freeman, M.M.,Seaman, M.S.,Rits-Volloch, S.,Hong, X.,Ho, D.D.,Chen, B. (deposition date: 2010-07-22, release date: 2010-12-22, Last modification date: 2011-07-13)
Primary citation	Freeman, M.M.,Seaman, M.S.,Rits-Volloch, S.,Hong, X.,Kao, C.Y.,Ho, D.D.,Chen, B. Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody. Structure, 18:1632-1641, 2010 Cited by PubMed: 21134642 DOI: 10.1016/j.str.2010.09.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation