3NZ0
Non-phosphorylated TYK2 kinase with CMP6
Summary for 3NZ0
Entry DOI | 10.2210/pdb3nz0/pdb |
Related | 3NYX |
Descriptor | Non-receptor tyrosine-protein kinase TYK2, 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE (3 entities in total) |
Functional Keywords | protein kinase, tyrosine phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 35295.40 |
Authors | Eigenbrot, C.,Ultsch, M. (deposition date: 2010-07-15, release date: 2010-10-20, Last modification date: 2023-09-06) |
Primary citation | Tsui, V.,Gibbons, P.,Ultsch, M.,Mortara, K.,Chang, C.,Blair, W.,Pulk, R.,Stanley, M.,Starovasnik, M.,Williams, D.,Lamers, M.,Leonard, P.,Magnuson, S.,Liang, J.,Eigenbrot, C. A new regulatory switch in a JAK protein kinase. Proteins, 79:393-401, 2011 Cited by PubMed: 21117080DOI: 10.1002/prot.22889 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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