3NSQ
Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron
Summary for 3NSQ
Entry DOI | 10.2210/pdb3nsq/pdb |
Related | 3NSP |
Descriptor | Retinoid X receptor, alpha, 1,8-dihydroxyanthracene-9,10-dione (3 entities in total) |
Functional Keywords | nuclear receptor retinoic x recepor alpha ligand binding domain antagonist danthron, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 53952.29 |
Authors | |
Primary citation | Zhang, H.,Zhou, R.,Li, L.,Chen, J.,Chen, L.,Li, C.,Ding, H.,Yu, L.,Hu, L.,Jiang, H.,Shen, X. Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286:1868-1875, 2011 Cited by PubMed: 21084305DOI: 10.1074/jbc.M110.166215 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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