3N5U
Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1
Summary for 3N5U
Entry DOI | 10.2210/pdb3n5u/pdb |
Descriptor | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Retinoblastoma-associated protein, MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | retinoblastoma, prb, rb, protein phosphatase-1, pp1, phosphatase, hydrolase, transcription regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P62136 Nucleus: P06400 |
Total number of polymer chains | 3 |
Total formula weight | 70566.22 |
Authors | Hirschi, A.M.,Cecchini, M.,Steinhardt, R.C.,Dick, F.A.,Rubin, S.M. (deposition date: 2010-05-25, release date: 2010-08-11, Last modification date: 2024-02-21) |
Primary citation | Hirschi, A.,Cecchini, M.,Steinhardt, R.C.,Schamber, M.R.,Dick, F.A.,Rubin, S.M. An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat.Struct.Mol.Biol., 17:1051-1057, 2010 Cited by PubMed: 20694007DOI: 10.1038/nsmb.1868 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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