3MZT
Protein-induced photophysical changes to the amyloid indicator dye, thioflavin T
Summary for 3MZT
Entry DOI | 10.2210/pdb3mzt/pdb |
Related | 3CIQ 3MYZ |
Descriptor | Beta-2-microglobulin, COPPER (II) ION, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, ... (4 entities in total) |
Functional Keywords | thioflavin t, amyloid, parkinson's, alzheimer's, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 6 |
Total formula weight | 72561.81 |
Authors | Wolfe, L.S.,Calabrese, M.F.,Nath, A.,Blaho, D.V.,Miranker, A.D.,Xiong, Y. (deposition date: 2010-05-13, release date: 2010-09-08, Last modification date: 2023-09-06) |
Primary citation | Wolfe, L.S.,Calabrese, M.F.,Nath, A.,Blaho, D.V.,Miranker, A.D.,Xiong, Y. Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc.Natl.Acad.Sci.USA, 107:16863-16868, 2010 Cited by PubMed: 20826442DOI: 10.1073/pnas.1002867107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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