3MQI
Human early B-cell factor 1 (EBF1) IPT/TIG domain
Summary for 3MQI
Entry DOI | 10.2210/pdb3mqi/pdb |
Descriptor | Transcription factor COE1, ETHYL MERCURY ION, trimethylamine oxide, ... (4 entities in total) |
Functional Keywords | immunoglobulin like fold, structural genomics, structural genomics consortium, sgc, transcription activator |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): Q9UH73 |
Total number of polymer chains | 3 |
Total formula weight | 32905.24 |
Authors | Siponen, M.I.,Lehtio, L.,Arrowsmith, C.H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Schueler, H.,Schutz, P.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Berglund, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-04-28, release date: 2010-05-26, Last modification date: 2024-02-21) |
Primary citation | Siponen, M.I.,Wisniewska, M.,Lehtio, L.,Johansson, I.,Svensson, L.,Raszewski, G.,Nilsson, L.,Sigvardsson, M.,Berglund, H. Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285:25875-25879, 2010 Cited by PubMed: 20592035DOI: 10.1074/jbc.C110.150482 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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