3ML5
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide
Summary for 3ML5
Entry DOI | 10.2210/pdb3ml5/pdb |
Descriptor | Carbonic anhydrase 7, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (4 entities in total) |
Functional Keywords | protein-inhibitor complex, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (Probable): P43166 |
Total number of polymer chains | 1 |
Total formula weight | 30396.38 |
Authors | Di Fiore, A.,Truppo, E.,Supuran, C.T.,Alterio, V.,Dathan, N.,Bootorabi, F.,Parkkila, S.,Monti, S.M.,De Simone, G. (deposition date: 2010-04-16, release date: 2011-03-02, Last modification date: 2023-11-01) |
Primary citation | Di Fiore, A.,Truppo, E.,Supuran, C.T.,Alterio, V.,Dathan, N.,Bootorabi, F.,Parkkila, S.,Monti, S.M.,De Simone, G. Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide Bioorg.Med.Chem.Lett., 20:5023-5026, 2010 Cited by PubMed: 20688517DOI: 10.1016/j.bmcl.2010.07.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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