3ML4
Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region
Summary for 3ML4
Entry DOI | 10.2210/pdb3ml4/pdb |
Descriptor | Protein Dok-7, Muscle, skeletal receptor tyrosine-protein kinase (3 entities in total) |
Functional Keywords | tyrosine phosphorylation, adapter protein, dimerization, signaling protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Peripheral membrane protein: Q18PE0 Membrane; Single-pass type I membrane protein (Potential): Q61006 |
Total number of polymer chains | 8 |
Total formula weight | 107416.77 |
Authors | Bergamin, E.,Hubbard, S.R. (deposition date: 2010-04-16, release date: 2010-07-14, Last modification date: 2011-07-13) |
Primary citation | Bergamin, E.,Hallock, P.T.,Burden, S.J.,Hubbard, S.R. The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization. Mol.Cell, 39:100-109, 2010 Cited by PubMed: 20603078DOI: 10.1016/j.molcel.2010.06.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report