3M1S
Structure of Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3
Summary for 3M1S
Entry DOI | 10.2210/pdb3m1s/pdb |
Descriptor | Glycogen synthase kinase-3 beta, Ruthenium pyridocarbazole (3 entities in total) |
Functional Keywords | transferase, enzyme inhibitor, organometallic compound, ruthenium center, ruthenium pyridocarbazole, atp-binding, kinase, phosphoprotein, serine/threonine-protein kinase, wnt signaling pathway, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P49841 |
Total number of polymer chains | 2 |
Total formula weight | 94595.30 |
Authors | Atilla-Gokcumen, G.E.,Di Costanzo, L.,Zimmermann, G.,Meggers, E. (deposition date: 2010-03-05, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Atilla-Gokcumen, G.E.,Di Costanzo, L.,Meggers, E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3beta J.Biol.Inorg.Chem., 16:45-50, 2011 Cited by PubMed: 20821241DOI: 10.1007/s00775-010-0699-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.134 Å) |
Structure validation
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