3LWN
Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex B)
Summary for 3LWN
Entry DOI | 10.2210/pdb3lwn/pdb |
Related | 3LW8 3LXR 3LYQ |
Descriptor | Transforming protein RhoA, IpgB2, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | ipgb2, rhoa, gtpase, gef, gef-gtpase-complex, wxxxe, ttss effector protein, bacterial gef, cytoskeleton dynamics, signaling protein-rhoa-binding protein complex, signaling protein/rhoa-binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 |
Total number of polymer chains | 4 |
Total formula weight | 86302.42 |
Authors | Klink, B.U.,Barden, S.,Heidler, T.V.,Borchers, C.,Ladwein, M.,Stradal, T.E.B.,Rottner, K.,Heinz, D.W. (deposition date: 2010-02-24, release date: 2010-03-31, Last modification date: 2023-11-01) |
Primary citation | Klink, B.U.,Barden, S.,Heidler, T.V.,Borchers, C.,Ladwein, M.,Stradal, T.E.B.,Rottner, K.,Heinz, D.W. Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285:17197-17208, 2010 Cited by PubMed: 20363740DOI: 10.1074/jbc.M110.107953 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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