3LCS
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Summary for 3LCS
Entry DOI | 10.2210/pdb3lcs/pdb |
Related | 3L9P 3LCT |
Descriptor | ALK tyrosine kinase receptor, STAUROSPORINE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | kinase domain, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, proto-oncogene, receptor, transmembrane, tyrosine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: Q9UM73 |
Total number of polymer chains | 1 |
Total formula weight | 39292.04 |
Authors | Lee, C.C. (deposition date: 2010-01-11, release date: 2010-08-04, Last modification date: 2023-09-06) |
Primary citation | Lee, C.C.,Jia, Y.,Li, N.,Sun, X.,Ng, K.,Ambing, E.,Gao, M.Y.,Hua, S.,Chen, C.,Kim, S.,Michellys, P.Y.,Lesley, S.A.,Harris, J.L.,Spraggon, G. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain. Biochem.J., 430:425-437, 2010 Cited by PubMed: 20632993DOI: 10.1042/BJ20100609 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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