3KRD
Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with Fellutamide B
Summary for 3KRD
Entry DOI | 10.2210/pdb3krd/pdb |
Related | 2FHG 2FHH 3H6F 3H6I 3HF9 3HFA |
Descriptor | Proteasome subunit alpha, Proteasome subunit beta, Fellutamide B, ... (5 entities in total) |
Functional Keywords | binding sites, mycobacterium tuberculosis, protein subunits, substrate specificity, hydrolase, proteasome, fellutamide b, inhibition, protease, threonine protease, virulence, autocatalytic cleavage, zymogen |
Biological source | Mycobacterium tuberculosis More |
Cellular location | Cytoplasm (By similarity): A5U4D5 A5U4D6 |
Total number of polymer chains | 42 |
Total formula weight | 738850.35 |
Authors | |
Primary citation | Lin, G.,Li, D.,Chidawanyika, T.,Nathan, C.,Li, H. Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome. Arch.Biochem.Biophys., 501:214-220, 2010 Cited by PubMed: 20558127DOI: 10.1016/j.abb.2010.06.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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