3KPS

Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLQAFTY a self peptide from the ABCD3 protein

Summary for 3KPS

• Entry DOI: 10.2210/pdb3kps/pdb
• Related: 3KPL 3KPM 3KPN 3KPO 3KPP 3KPQ 3KPR
• Descriptor: HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... (6 entities in total)
• Functional Keywords: hla b*4405, tcrpmhc structure, ternary complex, allorecognition, tcr recognition, self peptide, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, polymorphism, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30481; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 5
• Total formula weight: 94410.49

Authors

Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J. (deposition date: 2009-11-16, release date: 2009-12-22, Last modification date: 2023-09-06)

• Primary citation: Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J.; T cell allorecognition via molecular mimicry.; Immunity, 31:897-908, 2009; PubMed: 20064448; DOI: 10.1016/j.immuni.2009.09.025

Experimental method

X-RAY DIFFRACTION (2.7 Å)