3KKV
Structure of PKA with a protein Kinase B-selective inhibitor.
Summary for 3KKV
Entry DOI | 10.2210/pdb3kkv/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, PKI kinase inhibitor, (2S)-1-{[6-furan-3-yl-5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-(1H-indol-3-yl)propan-2-amine, ... (4 entities in total) |
Functional Keywords | protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Bos taurus (bovine) More |
Cellular location | Cytoplasm : P00517 |
Total number of polymer chains | 2 |
Total formula weight | 43476.34 |
Authors | Elkins, P.A.,Concha, N.O. (deposition date: 2009-11-06, release date: 2010-12-22, Last modification date: 2014-12-10) |
Primary citation | Lin, H.,Elkins, P.A.,Concha, N.O.,Heerding, D.,Wang, W.,Nidarmarthy, S.,Luengo, J.I.,Nelson, R.,Knick, V.B.,Choudhry, A.E. Structure of PKA with a protein Kinase B-selective inhibitor. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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