3K9Y

Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5

Summary for 3K9Y

• Entry DOI: 10.2210/pdb3k9y/pdb
• Related: 3K9V
• Descriptor: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE (3 entities in total)
• Functional Keywords: mitochondrial cytochrome p450, monotopic membrane protein, monooxygenase, vitamin d hormone metabolism, adrenodoxin, oxidoreductase
• Biological source: Rattus norvegicus (rat)
• Cellular location: Mitochondrion: Q09128
• Total number of polymer chains: 2
• Total formula weight: 114089.67

Authors

Annalora, A.J.,Goodin, D.B.,Hong, W.,Zhang, Q.,Johnson, E.F.,Stout, C.D. (deposition date: 2009-10-16, release date: 2009-12-15, Last modification date: 2023-09-06)

• Primary citation: Annalora, A.J.,Goodin, D.B.,Hong, W.X.,Zhang, Q.,Johnson, E.F.,Stout, C.D.; Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.; J.Mol.Biol., 396:441-451, 2010; PubMed: 19961857; DOI: 10.1016/j.jmb.2009.11.057

Experimental method

X-RAY DIFFRACTION (2.8 Å)