3K9M
Cathepsin B in complex with stefin A
Summary for 3K9M
Entry DOI | 10.2210/pdb3k9m/pdb |
Related | 1NB3 1STF |
Descriptor | Cathepsin B, Cystatin-A (3 entities in total) |
Functional Keywords | disulfide bond, glycoprotein, lysosome, protease, thiol protease, zymogen, thiol protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Lysosome : P07858 Cytoplasm : P01040 |
Total number of polymer chains | 4 |
Total formula weight | 77726.88 |
Authors | |
Primary citation | Renko, M.,Pozgan, U.,Majera, D.,Turk, D. Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft Febs J., 277:4338-4345, 2010 Cited by PubMed: 20860624DOI: 10.1111/j.1742-4658.2010.07824.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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