3K26
Complex structure of EED and trimethylated H3K4
Summary for 3K26
Entry DOI | 10.2210/pdb3k26/pdb |
Related | 3JPX 3JZG 3JZH 3JZN 3K27 |
Descriptor | Polycomb protein EED, HISTONE PEPTIDE (3 entities in total) |
Functional Keywords | wd40, structural genomics, nppsfa, national project on protein structural and functional analysis, structural genomics consortium, sgc, alternative initiation, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation, national project on protein structural and functional analyses |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O75530 |
Total number of polymer chains | 2 |
Total formula weight | 43721.89 |
Authors | Bian, C.B.,Xu, C.,Qiu, W.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-29, release date: 2009-12-15, Last modification date: 2011-07-13) |
Primary citation | Xu, C.,Bian, C.,Yang, W.,Galka, M.,Ouyang, H.,Chen, C.,Qiu, W.,Liu, H.,Jones, A.E.,Mackenzie, F.,Pan, P.,Li, S.S.,Wang, H.,Min, J. Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proc.Natl.Acad.Sci.USA, 107:19266-19271, 2010 Cited by PubMed: 20974918DOI: 10.1073/pnas.1008937107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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