3JBH
TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Summary for 3JBH
Entry DOI | 10.2210/pdb3jbh/pdb |
Related | 3DTP |
EMDB information | 1950 |
Descriptor | MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE (3 entities in total) |
Functional Keywords | myosin interacting-heads motif, cryo-em, thick filament, flexible docking, single particle reconstruction, iterative helical real space reconstruction (ihrsr), inter- and intramolecular interactions, myosin regulation, super-relaxation, striated muscle, tarantula, contractile protein |
Biological source | Aphonopelma (tarantula) More |
Total number of polymer chains | 12 |
Total formula weight | 1055858.66 |
Authors | Alamo, L.,Qi, D.,Wriggers, W.,Pinto, A.,Zhu, J.,Bilbao, A.,Gillilan, R.E.,Hu, S.,Padron, R. (deposition date: 2015-09-01, release date: 2016-03-09, Last modification date: 2024-02-21) |
Primary citation | Alamo, L.,Qi, D.,Wriggers, W.,Pinto, A.,Zhu, J.,Bilbao, A.,Gillilan, R.E.,Hu, S.,Padron, R. Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis. J. Mol. Biol., 428:1142-1164, 2016 Cited by PubMed: 26851071DOI: 10.1016/j.jmb.2016.01.027 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (20 Å) |
Structure validation
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