3ILZ
Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group
Summary for 3ILZ
Entry DOI | 10.2210/pdb3ilz/pdb |
Descriptor | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid (3 entities in total) |
Functional Keywords | nuclear receptor, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 31106.35 |
Authors | Aparicio, R.,Polikarpov, L.,Bleicher, L. (deposition date: 2009-08-07, release date: 2010-04-28, Last modification date: 2023-09-06) |
Primary citation | Bleicher, L.,Aparicio, R.,Nunes, F.M.,Martinez, L.,Gomes Dias, S.M.,Figueira, A.C.,Santos, M.A.,Venturelli, W.H.,da Silva, R.,Donate, P.M.,Neves, F.A.,Simeoni, L.A.,Baxter, J.D.,Webb, P.,Skaf, M.S.,Polikarpov, I. Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8:8-8, 2008 Cited by PubMed: 18237438DOI: 10.1186/1472-6807-8-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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