3II6

Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.

Summary for 3II6

• Entry DOI: 10.2210/pdb3ii6/pdb
• Descriptor: DNA repair protein XRCC4, DNA ligase 4, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: xrcc4, dna ligase iv, nhej, dna repair, brct, alternative splicing, coiled coil, dna damage, dna recombination, isopeptide bond, nucleus, phosphoprotein, polymorphism, ubl conjugation, atp-binding, cell cycle, cell division, disease mutation, dna replication, ligase, magnesium, metal-binding, nucleotide-binding, scid, ligase-dna binding protein complex, ligase/dna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q13426 P49917
• Total number of polymer chains: 6
• Total formula weight: 154211.77

Authors

Meesala, S.,Junop, M. (deposition date: 2009-07-31, release date: 2009-08-11, Last modification date: 2024-02-21)

• Primary citation: Wu, P.Y.,Frit, P.,Meesala, S.,Dauvillier, S.,Modesti, M.,Andres, S.N.,Huang, Y.,Sekiguchi, J.,Calsou, P.,Salles, B.,Junop, M.S.; Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4; MOL.CELL.BIOL., 11:3163-3172, 2009; PubMed: 19332554

Experimental method

X-RAY DIFFRACTION (2.4 Å)