3IF6

Crystal structure of OXA-46 beta-lactamase from P. aeruginosa

Summary for 3IF6

• Entry DOI: 10.2210/pdb3if6/pdb
• Descriptor: OXA-46 oxacillinase, L(+)-TARTARIC ACID, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: serine beta-lactamase, hydrolase
• Biological source: Pseudomonas aeruginosa; More
• Total number of polymer chains: 3
• Total formula weight: 94333.01

Authors

Docquier, J.D.,Benvenuti, M.,Calderone, V.,Giuliani, F.,Kapetis, D.,De Luca, F.,Rossolini, G.M.,Mangani, S. (deposition date: 2009-07-24, release date: 2010-03-16, Last modification date: 2023-11-22)

• Primary citation: Docquier, J.D.,Benvenuti, M.,Calderone, V.,Giuliani, F.,Kapetis, D.,De Luca, F.,Rossolini, G.M.,Mangani, S.; Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates; Antimicrob.Agents Chemother., 54:2167-2174, 2010; PubMed: 20145076; DOI: 10.1128/AAC.01517-09

Experimental method

X-RAY DIFFRACTION (2.4 Å)