3I7O
Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1
Summary for 3I7O
Entry DOI | 10.2210/pdb3i7o/pdb |
Related | 2B5M 3I7H 3I7K 3I7L 3I7N 3I7P 3I89 3I8C 3I8E |
Descriptor | DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1 (2 entities in total) |
Functional Keywords | ddb1, iqwd1, dcaf6, h-box motif, cytoplasm, dna damage, dna repair, dna-binding, host-virus interaction, nucleus, phosphoprotein, polymorphism, ubl conjugation, ubl conjugation pathway, alternative splicing, wd repeat, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q16531 Nucleus: Q58WW2 |
Total number of polymer chains | 2 |
Total formula weight | 128996.68 |
Authors | Li, T.,Robert, E.I.,Breugel, P.C.V.,Strubin, M.,Zheng, N. (deposition date: 2009-07-08, release date: 2009-12-08, Last modification date: 2023-09-06) |
Primary citation | Li, T.,Robert, E.I.,van Breugel, P.C.,Strubin, M.,Zheng, N. A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17:105-111, 2010 Cited by PubMed: 19966799DOI: 10.1038/nsmb.1719 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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