3I1Y
Crystal Structure of soluble epoxide Hydrolase
Summary for 3I1Y
Entry DOI | 10.2210/pdb3i1y/pdb |
Related | 3I28 |
Descriptor | Epoxide hydrolase 2, N-(3,3-diphenylpropyl)pyridine-3-carboxamide (3 entities in total) |
Functional Keywords | hydrolase, aromatic hydrocarbons catabolism, cytoplasm, detoxification, magnesium, metal-binding, peroxisome, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P34913 |
Total number of polymer chains | 1 |
Total formula weight | 63002.01 |
Authors | Farrow, N.A. (deposition date: 2009-06-28, release date: 2009-10-13, Last modification date: 2024-02-21) |
Primary citation | Eldrup, A.B.,Soleymanzadeh, F.,Taylor, S.J.,Muegge, I.,Farrow, N.A.,Joseph, D.,McKellop, K.,Man, C.C.,Kukulka, A.,De Lombaert, S. Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase. J.Med.Chem., 52:5880-5895, 2009 Cited by PubMed: 19746975DOI: 10.1021/jm9005302 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.469 Å) |
Structure validation
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