3HXG
Crystal structure of Schistsome eIF4E complexed with m7GpppA and 4E-BP
Summary for 3HXG
Entry DOI | 10.2210/pdb3hxg/pdb |
Related | 3HXI |
Descriptor | Eukaryotic Translation Initiation Factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | protein-mrna cap complex, acetylation, phosphoprotein, protein synthesis inhibitor, translation regulation, translation |
Biological source | Schistosoma mansoni More |
Total number of polymer chains | 2 |
Total formula weight | 25458.09 |
Authors | Liu, W.,Zhao, R.,Jones, D.N.M.,Davis, R.E. (deposition date: 2009-06-20, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Liu, W.,Zhao, R.,McFarland, C.,Kieft, J.,Niedzwiecka, A.,Jankowska-Anyszka, M.,Stepinski, J.,Darzynkiewicz, E.,Jones, D.N.,Davis, R.E. Structural insights into parasite EIF4E binding specificity for m7G and m2,2,7G mRNA cap. J.Biol.Chem., 284:31336-31349, 2009 Cited by PubMed: 19710013DOI: 10.1074/jbc.M109.049858 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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