3HWG

Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Fe-TrenCam-hopo2

Summary for 3HWG

• Entry DOI: 10.2210/pdb3hwg/pdb
• Related: 3HWD 3HWE 3HWF
• Descriptor: Neutrophil gelatinase-associated lipocalin, FE (III) ION, N,N'-{[(2-{[(2,3-dihydroxyphenyl)carbonyl]amino}ethyl)imino]diethane-2,1-diyl}bis(1-hydroxy-6-oxo-1,6-dihydropyridine-2 -carboxamide), ... (8 entities in total)
• Functional Keywords: lipocalin, siderophore, beta-barrel, disulfide bond, glycoprotein, pyrrolidone carboxylic acid, secreted, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 71627.94

Authors

Clifton, M.C. (deposition date: 2009-06-17, release date: 2010-06-02, Last modification date: 2023-09-06)

• Primary citation: Clifton, M.C.,Rupert, P.B.,Hoette, T.M.,Raymond, K.N.,Abergel, R.J.,Strong, R.K.; Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands; To be Published,

Experimental method

X-RAY DIFFRACTION (2.19 Å)