3HKV
Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide
Summary for 3HKV
Entry DOI | 10.2210/pdb3hkv/pdb |
Descriptor | Poly [ADP-ribose] polymerase 10, PHOSPHATE ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | parp, poly(adp-ribose) polymerase, nad, transferase, structural genomics, structural genomics consortium, sgc, cytoplasm, glycosyltransferase, nucleus, phosphoprotein, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleolus : Q53GL7 |
Total number of polymer chains | 2 |
Total formula weight | 49564.61 |
Authors | Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Kotzsch, A.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-26, release date: 2009-06-16, Last modification date: 2023-11-01) |
Primary citation | Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Kotzsch, A.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H. Human Poly(Adp-Ribose) Polymerase 10, Catalytic Fragment in Complex with an Inhibitor 3-Aminobenzamide To be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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