3HHI
Crystal Structure of Cathepsin B from T. brucei in complex with CA074
Summary for 3HHI
Entry DOI | 10.2210/pdb3hhi/pdb |
Related PRD ID | PRD_001032 |
Descriptor | Cathepsin B-like cysteine protease, [PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (7 entities in total) |
Functional Keywords | cysteine protease, occluding loop, hydrolase, protease, thiol protease |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 73318.60 |
Authors | Wu, P.,Kerr, I.D.,Brinen, L.S. (deposition date: 2009-05-15, release date: 2010-05-26, Last modification date: 2023-09-06) |
Primary citation | Kerr, I.D.,Wu, P.,Marion-Tsukamaki, R.,Mackey, Z.B.,Brinen, L.S. Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei Plos Negl Trop Dis, 4:e701-e701, 2010 Cited by PubMed: 20544024DOI: 10.1371/journal.pntd.0000701 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report