3H0V
Human AdoMetDC with 5'-Deoxy-5'-(dimethylsulfonio) adenosine
Summary for 3H0V
Entry DOI | 10.2210/pdb3h0v/pdb |
Related | 1I72 1I79 1I7B 1I7C 1I7M 1JEN 3H0W |
Descriptor | S-adenosylmethionine decarboxylase proenzyme, 1,4-DIAMINOBUTANE, 5'-deoxy-5'-(dimethyl-lambda~4~-sulfanyl)adenosine, ... (6 entities in total) |
Functional Keywords | adometdc with competitive substrate analogs, autocatalytic cleavage, decarboxylase, lyase, phosphoprotein, polyamine biosynthesis, pyruvate, s-adenosyl-l-methionine, schiff base, spermidine biosynthesis, zymogen |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 38800.11 |
Authors | Bale, S.,Brooks, W.H.,Hanes, J.W.,Mahesan, A.M.,Guida, W.C.,Ealick, S.E. (deposition date: 2009-04-10, release date: 2009-06-30, Last modification date: 2023-11-15) |
Primary citation | Bale, S.,Brooks, W.,Hanes, J.W.,Mahesan, A.M.,Guida, W.C.,Ealick, S.E. Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. Biochemistry, 48:6423-6430, 2009 Cited by PubMed: 19527050DOI: 10.1021/bi900590m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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