3GLT
Crystal Structure of Human SIRT3 with ADPR bound to the AceCS2 peptide containing a thioacetyl lysine
Summary for 3GLT
Entry DOI | 10.2210/pdb3glt/pdb |
Related | 3GLR 3GLS 3GLU |
Descriptor | NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, mitochondrial, ZINC ION, ... (6 entities in total) |
Functional Keywords | nad dependent deacetylase, sirtuin, intermediate trapped structure, thioacetyl peptide, hydrolase, metal-binding, mitochondrion, nad, polymorphism, transit peptide, zinc, alternative splicing, ligase, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion matrix: Q9NTG7 Q9NUB1 |
Total number of polymer chains | 2 |
Total formula weight | 33910.07 |
Authors | Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. (deposition date: 2009-03-12, release date: 2009-06-16, Last modification date: 2023-11-22) |
Primary citation | Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Choy, W.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284:24394-24405, 2009 Cited by PubMed: 19535340DOI: 10.1074/jbc.M109.014928 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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