3G6E
Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit
Summary for 3G6E
Entry DOI | 10.2210/pdb3g6e/pdb |
Related | 3G4S 3G71 |
Descriptor | 23S ribosomal RNA, 50S ribosomal protein L11P, 50S ribosomal protein L13P, ... (39 entities in total) |
Functional Keywords | large ribosomal subunit, antibiotic specificity, homoharringtonine, haloarcula marismortui, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc-finger, ribosome |
Biological source | Haloarcula marismortui More |
Cellular location | Cytoplasm : P12743 |
Total number of polymer chains | 31 |
Total formula weight | 1461627.50 |
Authors | Gurel, G.,Blaha, G.,Moore, P.B.,Steitz, T.A. (deposition date: 2009-02-06, release date: 2009-04-28, Last modification date: 2023-09-06) |
Primary citation | Gurel, G.,Blaha, G.,Moore, P.B.,Steitz, T.A. U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J.Mol.Biol., 389:146-156, 2009 Cited by PubMed: 19362093DOI: 10.1016/j.jmb.2009.04.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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