3G4P

OXA-24 beta-lactamase at pH 7.5

Summary for 3G4P

Entry DOI	10.2210/pdb3g4p/pdb
Related	2JC7
Descriptor	Beta-lactamase OXA-24 (2 entities in total)
Functional Keywords	b-lactamases, enzyme mechanism, carbapenem, resistance, hydrolase
Biological source	Acinetobacter baumannii
Total number of polymer chains	1
Total formula weight	27586.66
Authors	Santillana, E.,Romero, A. (deposition date: 2009-02-04, release date: 2010-02-23, Last modification date: 2023-11-22)
Primary citation	Bou, G.,Santillana, E.,Sheri, A.,Beceiro, A.,Sampson, J.M.,Kalp, M.,Bethel, C.R.,Distler, A.M.,Drawz, S.M.,Pagadala, S.R.,van den Akker, F.,Bonomo, R.A.,Romero, A.,Buynak, J.D. Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase J.Am.Chem.Soc., 132:13320-13331, 2010 Cited by PubMed: 20822105 DOI: 10.1021/ja104092z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation