3G2G
S437Y Mutant of human muscle pyruvate kinase, isoform M2
Summary for 3G2G
Entry DOI | 10.2210/pdb3g2g/pdb |
Descriptor | Pyruvate kinase isozymes M1/M2, SULFATE ION, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics consortium (sgc), single nucleotide polymorphism, snp, mutation, acetylation, allosteric enzyme, alternative splicing, glycolysis, kinase, magnesium, metal-binding, phosphoprotein, polymorphism, pyruvate, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P14618 |
Total number of polymer chains | 4 |
Total formula weight | 234197.16 |
Authors | Hong, B.,Dimov, S.,Allali-Hassani, A.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, c.,Weigelt, J.,Bochkarev, A.,Vedadi, M.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-31, release date: 2009-03-03, Last modification date: 2023-09-06) |
Primary citation | Allali-Hassani, A.,Hong, B.,Dimov, S.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, c.,Weigelt, J.,Bochkarev, A.,Park, H.,Vedadi, M. S437Y Mutant of human muscle pyruvate kinase, isoform M2 To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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