3FNE
Crystal structure of InhA bound to triclosan derivative 17
Summary for 3FNE
Entry DOI | 10.2210/pdb3fne/pdb |
Related | 3FNF 3FNG 3FNH |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL, ... (4 entities in total) |
Functional Keywords | inha, triclosan, tuberculosis, antibiotic resistance, fatty acid biosynthesis, lipid synthesis, nad, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 118257.65 |
Authors | Wang, F. (deposition date: 2008-12-24, release date: 2009-01-20, Last modification date: 2023-09-06) |
Primary citation | Freundlich, J.S.,Wang, F.,Vilcheze, C.,Gulten, G.,Langley, R.,Schiehser, G.A.,Jacobus, D.P.,Jacobs, W.R.,Sacchettini, J.C. Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4:241-248, 2009 Cited by PubMed: 19130456DOI: 10.1002/cmdc.200800261 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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