3FIG

Crystal Structure of Leucine-bound LeuA from Mycobacterium tuberculosis

Summary for 3FIG

Entry DOI	10.2210/pdb3fig/pdb
Related	1sr9
Descriptor	2-isopropylmalate synthase, LEUCINE, GLYCEROL, ... (5 entities in total)
Functional Keywords	tim barrel, amino-acid biosynthesis, branched-chain amino acid biosynthesis, leucine biosynthesis, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	141083.01
Authors	Koon, N.,Squire, C.J.,Baker, E.N. (deposition date: 2008-12-11, release date: 2008-12-23, Last modification date: 2023-11-01)
Primary citation	Koon, N.,Squire, C.J.,Baker, E.N. Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis. Proc.Natl.Acad.Sci.USA, 101:8295-8300, 2004 Cited by PubMed: 15159544 DOI: 10.1073/pnas.0400820101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation