3FHT

Crystal structure of human Dbp5 in complex with AMPPNP and RNA

Summary for 3FHT

• Entry DOI: 10.2210/pdb3fht/pdb
• Related: 3FHC
• Descriptor: ATP-dependent RNA helicase DDX19B, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: dbp5, dead-box helicase, rna dependent atpase, mrna export, nucleocytoplasmic transport, nup214, can, nup159, ddx19b, nuclear pore, gle1, atp-binding, helicase, hydrolase, membrane, mrna transport, nuclear pore complex, nucleotide-binding, nucleus, phosphoprotein, protein transport, rna-binding, translocation, transport, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q9UMR2
• Total number of polymer chains: 4
• Total formula weight: 100708.07

Authors

von Moeller, H.,Conti, E. (deposition date: 2008-12-10, release date: 2009-02-17, Last modification date: 2023-11-01)

• Primary citation: von Moeller, H.,Basquin, C.,Conti, E.; The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner; Nat.Struct.Mol.Biol., 16:247-254, 2009; PubMed: 19219046; DOI: 10.1038/nsmb.1561

Experimental method

X-RAY DIFFRACTION (2.2 Å)