3FGQ

Crystal structure of native human neuroserpin

Summary for 3FGQ

Entry DOI	10.2210/pdb3fgq/pdb
Descriptor	Neuroserpin, GLYCEROL (3 entities in total)
Functional Keywords	serpin, polymerization, dementia, tpa, inhibitor, disease mutation, glycoprotein, protease inhibitor, secreted, serine protease inhibitor, hydrolase inhibitor
Biological source	Homo sapiens (Human)
Cellular location	Secreted: Q99574
Total number of polymer chains	2
Total formula weight	90390.27
Authors	Takehara, S.,Yang, X.,Mikami, B.,Onda, M. (deposition date: 2008-12-08, release date: 2009-04-28, Last modification date: 2023-11-01)
Primary citation	Takehara, S.,Onda, M.,Zhang, J.,Nishiyama, M.,Yang, X.,Mikami, B.,Lomas, D.A. The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability J.Mol.Biol., 388:11-20, 2009 Cited by PubMed: 19285087 DOI: 10.1016/j.jmb.2009.03.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation