3FFS
The Crystal Structure of Cryptosporidium parvum Inosine-5'-Monophosphate Dehydrogenase
Summary for 3FFS
| Entry DOI | 10.2210/pdb3ffs/pdb |
| Descriptor | Inosine-5-monophosphate dehydrogenase (1 entity in total) |
| Functional Keywords | beta-alpha barrel, tim fold, oxidoreductase |
| Biological source | Cryptosporidium parvum |
| Cellular location | Cytoplasm : Q8T6T2 |
| Total number of polymer chains | 4 |
| Total formula weight | 172537.05 |
| Authors | Riera, T.V.,D'Aquino, J.A.,Lu, J.,Petsko, G.A.,Hedstrom, L. (deposition date: 2008-12-04, release date: 2009-12-15, Last modification date: 2023-09-06) |
| Primary citation | Macpherson, I.S.,Kirubakaran, S.,Gorla, S.K.,Riera, T.V.,D'Aquino, J.A.,Zhang, M.,Cuny, G.D.,Hedstrom, L. The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity J.Am.Chem.Soc., 132:1230-1231, 2010 Cited by PubMed: 20052976DOI: 10.1021/ja909947a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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